The Native API is a lightweight application programming interface (API) used by Windows NT and user mode applications. This API is used in the early stages of Windows NT startup process, when other components and APIs are still unavailable. Therefore, a few Windows components, such as the Client/Server Runtime Subsystem (CSRSS), are implemented using the Native API. The Native API is also used by subroutines such as those in kernel32.dll that implement the Windows API, the API based on which most of the Windows components are created.

Most of the Native API calls are implemented in ntoskrnl.exe and are exposed to user mode by ntdll.dll. The entry point of ntdll.dll is LdrInitializeThunk. Native API calls are handled by the kernel via the System Service Descriptor Table (SSDT).